ADC值鉴别软组织肿瘤良恶性的价值

目的探讨ADC值在鉴别软组织肿瘤良、恶性诊断中的应用价值。方法 29例经手术病理证实的软组织良、恶性肿瘤,行常规MRI平扫和DWI,扩散敏感因子(b值)分别为0、800s/mm2,测量病变的表观弥散系数(ADC)值。结果 MRI联合DWI对软组织肿瘤的良恶性诊断率较高。12例恶性肿瘤的平均ADC值为(0.92±0.22)×10-3mm2/s,17例良性肿瘤的平均ADC值为(1.81±0.28)×10-3mm2/s,两者之间的差异有统计学意义。结论 ADC值在鉴别软组织肿瘤良恶性的诊断中具有重要价值。

Evaluation of Apparent Diffusion Coefficient for the Differential Diagnosis of Soft-tissue Tumors

Objective To explore the potential value of apparent diffusion coefficient(ADC) in characterizing soft-tissue tumors.Methods The apparent diffusion coefficient(ADC) values was obtained by 29 histologically proven soft-tissue tumor cases using diffusion-weighted spin-echo sequences,the b values of diffusion were 0 and 800s/mm2.Results There is a slightly higher coincidence rate of soft tissue tumor qualitative diagnosis in the combination of conventional MRI scan and DWI than single one.The ADC values of the malignant tumors(mean±SD) were(0.92±0.22)×10-3mm2/s,benign lesions is(1.81±0.28)×10-3mm2/s.There was significant statistic difference in ADC values between benign lesions and malignant lesions.Conclusion Diffusion-weighted MRI has important value in differentiating benign softtissue tumors from malignant ones.