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Effect of immunization against rabies on γ-aminobutyric metabolism in the animal brain
Authors:T. M. Khizhnyakova  M. Sh. Promyslov  L. P. Gorshunova
Abstract:Subcutaneous injection of fixed rabies virus into albino rats weighing 100–120 g is followed by a decrease in thegamma-aminobytyric acid (GABA) concentration in the animals' brains. An increase in the activity of GABA-agr-ketoglutarate transaminase also is observed in the brain tissue of animals vaccinated against rabies.Laboratory of Immunopathology, D. I. Ivanovskii Institute of Virology. Laboratory of Biochemistry, N. N. Burdenko Institute of Neurosurgery, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician V. D. Timakov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 81, No. 2, pp. 184–185, February, 1976.
Keywords:rabies    /content/t747q56101wj0557/xxlarge947.gif"   alt="  gamma"   align="  MIDDLE"   BORDER="  0"  >-aminobutyric acid (GABA)  immunization
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