| 含莫西沙星的抗痨方案治疗耐多药肺结核的疗效观察 |
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| 引用本文： | 王静飞,高春荣.含莫西沙星的抗痨方案治疗耐多药肺结核的疗效观察[J].中国临床药学杂志,2010(1):33-35. |
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| 作者姓名： | 王静飞 高春荣 |
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| 作者单位： | 浙江省宁波市第四医院肺一科; |
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| 摘 要： | 目的观察和评估含莫西沙星的化疗方案在耐多药肺结核治疗中的疗效。方法将97例耐多药肺结核患者分为治疗组（n=48）和对照组（n=49）。对照组采用的化疗方案为阿米卡星、利福喷丁、对氨基水杨酸钠异烟肼、丙硫异烟胺、吡嗪酰胺；治疗组在此基础上加莫西沙星，疗程为21个月。结果共有93例患者完成化疗疗程，其中治疗组46例，对照组47例。疗程结束时痰菌阴转率治疗组为87％，对照组为59．6％，治疗组明显高于对照组（P〈0．01）。结论含莫西沙星方案治疗耐多药肺结核有助于痰菌阴转和病变吸收好转，药物不良反应少。
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| 关 键 词： | 耐多药肺结核 莫西沙星 临床疗效 |
Treatment effect of regimen which contains the moxifloxcin on multi-drug resistant pulmonary tuberculosis |
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| WANG Jingfei,GAO Chunrong.Treatment effect of regimen which contains the moxifloxcin on multi-drug resistant pulmonary tuberculosis[J].Chinese Journal of Clinical Pharmacy,2010(1):33-35. |
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| Authors: | WANG Jingfei GAO Chunrong |
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| Institution: | First Department of Lung Disease/a>;The Fourth Hospital of Ningbo/a>;Zhejiang Province/a>;Ningbo 315031/a>;China |
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| Abstract: | AIM To observe and evaluate the treatment effect of the regimen which contains the moxifloxcin on multi-drug resistant pulmonary tuberculosis(MDR-TB).METHODS Ninety-seven MDR-TB patients were randomly divided into two groups.Fouty-eight patients in the treatment group treated with moxifloxacin(M) amikacin(A),rifanpentine (L),isoniazid aminosalicylate(D),pyrazinamide(Z) and protionamide(Pt).Fouty-nine patients in the control group treated with A,L,D,Z and Pt.The duration of treatment was twenty-one months.RE... |
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| Keywords: | multi-drug resistant pulmonary tuberculosis moxifloxacin treatment effect |
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