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Statin therapy for prevention of coronary artery disease. The earlier the better or the longer the better?
Authors:Hallvard Holdaas
Institution:Section of Nephrology, Medical Department, The National Hospital, Sognsvannsvn 20, N-0027 Oslo, Norway
Abstract:Cholesterol lowering with statin therapy has been shown to reducecardiovascular events in a variety of patient categories, rangingfrom patients with established cardiovascular disease to high-riskindividuals with no previous history.1 The degree of benefitrelates primarily to a patient's absolute risk of cardiovascularevents and to the absolute reduction in low-density lipoprotein(LDL)-cholesterol. The optimal intensity of
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