| 脑缺血-再灌注后细胞凋亡的Caspase-3机制 |
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| 引用本文： | 陈蓉,林燕,张英. 脑缺血-再灌注后细胞凋亡的Caspase-3机制[J]. 黑龙江医学, 2005, 29(11): 823-825 |
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| 作者姓名： | 陈蓉 林燕 张英 |
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| 作者单位： | 四川省泸州医学院病理生理教研室,四川,泸州,646000;四川省泸州医学院病理生理教研室,四川,泸州,646000;四川省泸州医学院病理生理教研室,四川,泸州,646000 |
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| 摘 要： | 脑缺血-再灌流后细胞凋亡的发生与Caspase-3密切相关。缺血-再灌流后,自由基的产生、细胞器的损伤、促凋亡因子释放等都会使Caspase-3 mRNA表达增强诱导凋亡。
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| 关 键 词： | 脑缺血-再灌流 细胞凋亡 Caspase-3 机制 |
| 文章编号： | 1004-5775(2005)11-0823-03 |
| 收稿时间： | 2005-09-08 |
| 修稿时间： | 2005-09-08 |
Mechanism on the Neuronal Apoptosis and the Expression Caspase-3 gene after Focal Cerebral Ischemia Reperfusion |
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| CHEN Rong,LIN Yan,ZHANG Ying. Mechanism on the Neuronal Apoptosis and the Expression Caspase-3 gene after Focal Cerebral Ischemia Reperfusion[J]. Heilongjiang Medical Journal, 2005, 29(11): 823-825 |
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| Authors: | CHEN Rong LIN Yan ZHANG Ying |
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| Affiliation: | Department ofPathophysiology, Luzhou Medical College, Sicuan 646000, China |
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| Abstract: | The neuronal apoptosis after focal cerebral ischemia reperfusion is correlated intimately with the expression of caspase-3 gene,the production of free redicle,the injury of cellular organs,the release of crowded apoptosis factors and so on that can enhance the expression of caspase-3,which induce the neuronal apoptosis. |
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| Keywords: | Cerebral Ischemia Reperfusion Apoptosis Caspase-3 Mechanism |
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