乌鲁木齐市40~69岁上消化道癌高危人群内窥镜筛查结果分析

[目的]对2014～2015年度乌鲁木齐市上消化道癌高危人群进行筛查,探讨筛查的依从性、内窥镜和病理活检对上消化道疾病的检出率,以及上消化道癌和癌前病变的早诊率.[方法]在40～69岁乌鲁木齐市居民中,采用问卷调查法筛查出上消化道癌高危人群;经知情同意后,进行内窥镜检查并取活检,对检查结果进行分析.[结果]问卷调查共筛查出上消化道癌高危人群9978人,实际完成筛查1548例,依从性为15.5％;其中,女性依从性(16.4％)高于男性(14.5％),60～69岁年龄组的依从性最高(17.0％),差异有统计学意义(P＜0.05).内窥镜检出胃部病变338例(21.8％),食管病变106例(6.8％).病理检出胃部病变655例(42.3％),食管病变60例(3.9％).上消化道癌及癌前病变检出率为0.26％,早诊率为25％;其中胃癌及癌前病变检出1例,食管癌及癌前病变检出3例.[结论]以问卷调查为基础,结合内窥镜及病理检查,能提高早期发现、早期诊断和早期治疗的比例,降低上消化道癌发病率和死亡率,从而提高患者生活质量,减轻个人和社会经济负担.

Endoscopic Screening of Upper Digestive Tract Cancer Among High-risk Population in Urumqi

[Purpose] To screen the high risk population of upper digestive tract cancer in Urumqi in 2014～2015.[Methods] High risk population of upper digestive tract cancer was screened with questionnaire survey among Urumqi residents aged 40～69 during 2014 to 2015,then the endoscopic examination and biopsy were performed in high risk subjects.[Results] Total 9978 subjects were identified as high risk of upper digestive tract cancer according to questionnaire survey,among whom 1548 cases underwent endoscopic examination.The overall compliance rate was 15.5％,the compliance of females was high than males (16.4％ vs.14.5％,P＜0.05),and subjects in age group of 60 to 69 had a highest compliance(17％).There were 338 gastric lesions(21.8％) and 106 esophageal lesions (6.8％) detected by endoscopic examinations;while there were 655 gastric lesions(42.3％) and 60 esophageal lesions(3.9％) confirmed pathologically.Four cases of upper gastrointestinal cancer and precancerous lesion were detected (0.26％) with an early diagnosis rate of 25％.[Conclusion] Combination of endoscopic and pathologic examination can improve the early discovery of upper digestive tract cancer.