蒲田胶囊止痛止血作用的实验研究

目的：通过动物实验探讨临床中行之有效的蒲田胶囊治疗子宫内膜异位症痛经、月经过多、经期延长的作用机理。方法：应用小鼠热板法、扭体法观察蒲田胶囊的镇痛作用，应用玻片法观察蒲田观察胶囊的止血作用。结果：蒲田胶囊对化学刺激引起的小鼠疼痛有一定的镇痛作用，并有缩短小鼠的凝血时间从而有促进凝血的作用。结论：分析现有药理研究成果及本实验结果后认为：蒲田胶囊通过增加血小板数、促进凝血酶的生成、影响中枢神经而起到镇痛、止血作用。

EXPERIMENTAL STUDY ON ANALGESIC AND HEMOSTATIC EFFECTS OF PUTIAN CAPSULE

Objective:In this research, analgesic and hemostatic effects of Putian capsule were observed.Methods:The mouse were divided into four groups randomly: normal control group, LuTongDing group, high and low dosage group of Putian capsule. The mouse hot plate method and torsion test were applied to measure threshold of pain in each group. While slide method adopted to observe the hemostatic time in Putian capsule group and normal group.Results:The threshold of pain caused by chemical stimulation was raised significantly in Putian capsuie group compared with control group, while there were no significant differences on the threshold of pain caused by hot stimulation between the Putian capsule group and normal group. In the mean time, the hemostatic time were reduced significantly in the Putian capsule group compared with control group.Conclusions:It is suggested that Putian capsule has a certain analgesic effect on the pain on mouse induced by chemical stimulation, and reduce the clotting and consequently promote the coagulation. It may be possible mechanism of curing endometriosis with Putian capsule in clinic.