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碱性成纤维细胞生长因子在自体脂肪游离移植中血管生成的早期作用
引用本文:廖天安,谢富生,符起亚,王琼超. 碱性成纤维细胞生长因子在自体脂肪游离移植中血管生成的早期作用[J]. 中国修复重建外科杂志, 1994, 0(4)
作者姓名:廖天安  谢富生  符起亚  王琼超
作者单位:海口市海南医学院附属医院口腔科,海口市海南医学院附属医院病理教研室
摘    要:应用碱性成纤维细胞生长因子于自体脂肪游离移植,以刺激移植体早期的血管形成。移植脂肪在对照侧单纯加入纤维蛋白;实验侧加入含有bFGF的纤维蛋白。动物术后存活5、7、10天。各期动物经心脏主动脉插管,灌注墨汁。结果显示各期实验侧移植物中血管生成密度均明显高于对照侧。

关 键 词:碱性成纤维细胞生长因子脂肪移植,血管生长

ABSTRACTSTHE EARLY EFFECT OF BASIC FIBROBLASTIC GROWTH FACTOR ON THE STIMULATIONOF REVASCULARIZATION OF AUTOGENOUS FREE FAT GRAFTS
/. ABSTRACTSTHE EARLY EFFECT OF BASIC FIBROBLASTIC GROWTH FACTOR ON THE STIMULATIONOF REVASCULARIZATION OF AUTOGENOUS FREE FAT GRAFTS[J]. Chinese journal of reparative and reconstructive surgery, 1994, 0(4)
Authors:/
Abstract:he basic fibroblastic growth factor (bFGF) was employed to stimulate the earlyrevascularization of the autogenous free fat grafts. In the experimental group the fibrin containingbFGF was mixed to the fat to be implanted, and the fat containing the fibrin only was used as thecontrol. The animals were perfused with Chenese ink through intubation to the aorta via the heart at 5 ,7, and 10 days after operation. The vascularizarion was significantly increased at the bFGF side ascompared with that of the control at different period of time following operation.
Keywords:: Basic fibroblastic growth factor  Fat graft  Revascularization.
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