胰岛素抵抗性高血压病的发病机制与治疗

胰岛素抵抗是一独立的心血管病危险因素,它与高血压、动脉粥样硬化和冠状动脉粥样硬化性心脏病等有密切关系。研究发现,原发性高血压患者的胰岛素抵抗主要表现在葡萄糖的摄取和利用上。随着研究的不断深入,胰岛素抵抗与高血压病的关系已成为心血管领域的研究热点,本文从胰岛素抵抗的概念、产生机制、检测方法、胰岛素抵抗在高血压病发生、发展中的作用机制,以及抗高血压药物对胰岛素抵抗的影响3个方面进行阐述。

The Pathogenesy and Treatment of Hypertension Disease with Insulin Resistance

Insulin resistance is an independent risk factor of cardiovascular disease, which is closely related to hypertension, atherosclerosis, and coronary atherosclerotic heart disease. Research indicates that the insulin resistance in patients with primary hypertension is mainly shown in the ingestion and utilization of glucose. The relationship between insulin resistance and hypertension has been a hot spot in the field of cardiology as they made intensive studies, and it will be elucidated in the following three aspects, the definition and mechanism and detection of insulin resistance, the mechanism of insulin resistance in the development of hypertension, and the effect of antihypertensive drugs in insulin resistance.