不同女性人群解脲脲原体检测结果分析

目的:对广州地区解脲脲原体(Uu)在不同女性人群的检测结果及其对抗生素的敏感性进行分析,为临床合理应用抗生素治疗其感染提供依据。方法:采集生殖道炎症患者及健康体检女性两组人群的生殖道分泌物标本,用法国生物梅里埃公司IST2试剂盒进行Uu培养、鉴定和药敏试验,结合临床资料,对两组人群的Uu检测结果进行分析。结果:Uu阳性率生殖道炎症组为38.7%,健康体检组为33.5%,两组阳性率差异无统计学意义(P>0.05),且Uu在各年龄段女性定植无差异;生殖道炎症组Uu≥104 CFU/ml的例数明显高于健康体检组,两组Uu≥104 CFU/ml检出率比较差异有统计学意义(P<0.01);药敏结果显示除环丙沙星和氧氟沙星外,其余抗生素对Uu均有较好的抗菌活性(敏感性均>70%)。结论:Uu为女性生殖道常见寄生物,应慎重判断其致病性,合理应用抗生素治疗其感染。

Analysis on the detection results of ureaplasma urealyticum among different female populations

Objective:To analyze the detection results of ureaplasma urealyticum among different female populations in Guangzhou region and the drug sensitivity of ureaplasma urealyticum,provide a basis for reasonable application of drugs for treatment of ureaplasma urealyticum infection in clinic.Methods:The samples of genital secretion were collected from the patients with genital tract inflammation and normal women receiving physical examination,IST 2 kit(BioMérieux) was used for culture,differentiation and drug sensitive test of ureaplasma urealyticum,then the detection results of ureaplasma urealyticum in the two groups were analyzed combined with clinical data.Results:The positive rates of ureaplasma urealyticum in genital tract inflammation group and physical examination group were 38.7% and 33.5%,respectively,there was no significant difference between the two groups(P>0.05),and there was no significant difference in infection rate among the women of different age groups;the number of women with ureaplasma urealyticum≥104 CFU/ml in genital tract inflammation group was significantly higher than that in physical examination group,there was significant difference in the detection rate of women with ureaplasma urealyticum≥104 CFU/ml between the two groups(P<0.01).The results of drug sensitive test showed that except ciprofloxacin and ofloxacin,the antimicrobial activity of other antibiotics was good for ureaplasma urealyticum(the sensitivity>70%).Conclusion:Ureaplasma urealyticum is a common parasite in female genital tract,its pathogenicity should be judged carefully,and antibiotics should be provided to the women with ureaplasma urealyticum infection reasonably.