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65例育龄期妇女垂体泌乳素微腺瘤治疗分析
引用本文:王雪鹏,张开治,房向阳.65例育龄期妇女垂体泌乳素微腺瘤治疗分析[J].中国妇幼保健,2011,26(34):5313-5315.
作者姓名:王雪鹏  张开治  房向阳
作者单位:1. 北华大学第一附属医院神经外二科,吉林,吉林,132011
2. 吉林大学中日联谊医院神经外二科
摘    要:目的:探讨经鼻蝶窦入路显微手术及溴隐亭药物治疗育龄期妇女垂体泌乳素微腺瘤的临床治疗效果。方法:研究2007年4月-2010年11月收治的65例育龄期女性垂体泌乳素微腺瘤患者,经鼻蝶显微手术40例,药物(溴隐亭)保守治疗25例,对手术治疗和药物治疗后患者月经恢复情况、血PRL变化及生育情况进行统计学分析。结果:手术治疗和药物治疗后月经恢复情况、血PRL变化差异无统计学意义(P>0.05);手术治疗和药物治疗后生育情况差异有统计学意义(P<0.05),手术组优于药物治疗组。结论:在育龄期女性垂体泌乳素微腺瘤的治疗上,经鼻蝶显微手术治疗优于药物(溴隐亭)保守治疗,但在实际治疗方案选择上应根据患者具体情况进行个性化治疗。

关 键 词:垂体泌乳素微腺瘤  显微手术  溴隐亭

Treatment and analysis on 65 women of childbearing age with pituitary microprolactinoma
WANG Xue-Peng,ZHANG Kai-Zhi.Treatment and analysis on 65 women of childbearing age with pituitary microprolactinoma[J].Maternal and Child Health Care of China,2011,26(34):5313-5315.
Authors:WANG Xue-Peng  ZHANG Kai-Zhi
Institution:WANG Xue-Peng,ZHANG Kai-Zhi.The Second Department of Neurosurgery,the First Affiliated Hospital of BeiHua University,Jilin 132011,Jilin,China
Abstract:Objective:To explore the clinical curative effect of nasal transsphenoidal microsurgery and bromocriptine in treatment of pituitary microprolactinoma among the women of childbearing age.Methods:65 women of childbearing age with pituitary microprolactinoma who were treated in the hospital from April 2007 to November 2010 were selected,40 women were treated with nasal transsphenoidal microsurgery and 25 women were treated with bromocriptine,the recoveries of menstruation after treatment,the changes of blood p...
Keywords:Pituitary microprolactinoma  Microsurgery  Bromocriptine  
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