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正交试验法优选益宫散结口服液水煎醇沉工艺
引用本文:彭燕,张洪,文为.正交试验法优选益宫散结口服液水煎醇沉工艺[J].中国药师,2006,9(10):924-925.
作者姓名:彭燕  张洪  文为
作者单位:武汉大学人民医院药学部,武汉,430060
摘    要:目的:优选益宫散结口服液的提取工艺。方法:采用正交试验法,以芍药苷含量和干膏得率为指标,考察煎煮次数、煎煮时问、加水量及醇沉浓度对提取率的影响。结果:最佳提取工艺为加8倍量水煎煮3次,每次1 h,醇沉浓度为50%。结论:优化后的提取方法稳定,提取效率较高。

关 键 词:益宫散结口服液  正交试验法  芍药苷
文章编号:1008-049X(2006)10-0924-02
收稿时间:2005-12-23
修稿时间:2006-01-16

Optimize for Water Decoction Extration Process of Yigongsanjie Oral Solution by Orthogonal Design
Peng Yan,Zhang Hong,Wen Wei.Optimize for Water Decoction Extration Process of Yigongsanjie Oral Solution by Orthogonal Design[J].China Pharmacist,2006,9(10):924-925.
Authors:Peng Yan  Zhang Hong  Wen Wei
Abstract:Objective: To select the best water decoction extration process of Yigongsanjie oral solution. Method: The orthogonal design was used and the content of paconiflorin and total extractum were taken as determination factors. Result: The best extract process was as three times by 60 minutes adding 8 fold of water. The concentration of alcohol was addied to 50%. Conclusion: The extraction process was stable and good performance.
Keywords:Yigongsanjie oral solution  Orthogonal design  Paconiflorin
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