多模态影像神经导航联合术中超声在切除颅内胶质瘤中的应用

目的 探讨多模态影像神经导航联合术中超声在切除颅内胶质瘤中的临床应用及其价值.方法 回顾性分析本院2007年12月31日至2014年6月30日在多模态影像神经导航联合术中超声辅助下手术治疗的42例颅内胶质瘤患者临床资料,对比手术前后胶质瘤切除程度及胶质瘤继发癫痫的控制情况.结果 全部患者术后无血肿、感染、偏瘫.术后48 h复查MRI,结果显示肿瘤全切除34例,大部切除8例.术后1年评估癫痫控制情况,Engel's Ⅰ级17例,Engel'sⅡ级11例,Engel'sⅢ级5例.在保护神经功能的同时,切除肿瘤,控制癫痫发作,临床效果显著.结论 多模态影像神经导航联合术中超声可以实现最大程度切除肿瘤及致痫灶,降低术后神经功能障碍的发生率.

Clinical value of multimodal image guided neuronavigation combined with intraoperative ultrasound in resection of intracranial gliomas: report of 42 cases

Objective To investigate the clinical value of multimodal neuronavigation combined with intraoperative ultrasound in the resection of intracranial gliomas.Methods A retrospective analysis was carried out on 42 patients undergoing intracranial glioma surgery in our hospital from December 31 st,2007 to June 30th 2014 with the aid of multimodal neuronavigation combined with intraoperative ultrasound.Their clinical data were collected and compared before and after surgery,and the resection of glioma and control of glioma-associated epilepsy were investigated.Results No hematoma,infection or hemiplegia occurred in all the patients.At 48 h after operation,MRI and MRI showed complete resection in 34 cases and subtotal resection in 8 cases.In 1 year after operation,17 case obtained Engel's class Ⅰ,11 cases Engel's class Ⅱ,and 5 cases Engel's class Ⅲ in the evaluation of seizure control.This approach had significant clinical value in protection of nerve function,resection of tumor,and control of epileptic seizure.Conclusion Multimodal neuroimaging combined with intraoperative ultrasound is helpful to make maximum resection of tumor and epileptic focus and to reduce the incidence of postoperative neurological dysfunction.