基于心率的主动脉血泵流量控制

背景：随着人工心脏研究和应用的不断发展，在装置的性能上，人们希望它能符合自然心脏的生理机制，满足受者的生理需求。目的：针对主动脉血泵的控制，提出了基于心率的血泵流量控制算法。方法：通过分析心率与流量之间的关系，建立了心率与流量的关系模型，并根据人体心率流量关系验证血泵流量模型的准确性。运用PID控制算法对血泵流量进行控制。结果与结论：仿真结果表明血泵可以实现快速稳定的输出。当心率为75次/min时，流量能达到5.01L／min；在50-120次/min心率范围内，流量会随着心率的提高而增大；当心率大小于50次／min或于120次／min时，血泵工作在恒流量状态下。通过PID控制，可使流量在O.1s内跟踪上参考流量。基于心率的血泵流量模型能反映人体血流量需求，通过控制血泵可实现满足人体需求的流量输出。

Flow control of intra aorta pump based on heart rate

BACKGROUND： With the development of the research and application of artificial heart, people hope that it can accord with physiological mechanism of natural heart and meet demand of human body in device performance. OBJECTIVE： For the control of intra-aorta pump, this paper proposed the flow control algorithm based on heart rate. METHODS： Utilizing the PID control algorithm to maintain the output flow satisfy the physical needs of patients. Simulation results show the accuracy of the algorithm to achieve fast and stable flow blood pump output. RESULTS AND CONCLUSION： When the heart rate was of 75 times per minute, blood pump flow rate could reach 5.01 L/min; blood pump flow gradually increased with the heart rate when the heart rate was in the range from 50 to 120 times per minute; blood pump kept constant flow state when the heart rate less than 50 times per minute or more than 120 times per minute. Through PID control, the actual flow rate tracks the reference one within 0.1 s. The blood pump flow model based on heart rate can reflect the needs of human blood flow. The control algorithm can achieve stable flow blood pump output, to keep pace human needs of patients.