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转筋草中化学成分研究
引用本文:肖会君,李晨阳,唐生安,秦楠,段宏泉. 转筋草中化学成分研究[J]. 中国中药杂志, 2013, 38(3): 350-353
作者姓名:肖会君  李晨阳  唐生安  秦楠  段宏泉
作者单位:天津医科大学药学院基础医学研究中心天津市临床药物关键技术重点实验室,天津,300070
基金项目:国家自然科学基金项目(81072540)
摘    要:研究转筋草Pachysandra terminalis化学成分.综合运用硅胶柱色谱、凝胶柱色谱、制备HPLC色谱等分离色谱法分离纯化转筋草中的化学成分,采用NMR和质谱等有机波谱学方法鉴定各单体化合物的结构.从转筋草中分离得到5个化合物,鉴定为2-甲基-3-亚甲基-1,2,5-戊三醇(1),4-甲基-3-亚甲基-1,2,5-戊三醇(2),4-甲基-3-亚甲基-1,2,5-戊三醇-5-O-β-D-吡喃葡萄糖苷(3),4-甲基-3-亚甲基-1,2,5-戊三醇-1-O-β-D-吡喃葡萄糖苷(4),(7S,8R,8’R)-(+)-落叶松醇-9-O-β-D-吡喃葡萄糖苷(5).其中化合物1~4为新化合物,化合物5为首次从该植物中分离得到.

关 键 词:板凳果属  转筋草  化学成分
收稿时间:2012-11-05

Chemical constituents from Pachysandra terminalis
XIAO Hui-jun,LI Chen-yang,TANG Sheng-an,QIN Nan and DUAN Hong-quan. Chemical constituents from Pachysandra terminalis[J]. China Journal of Chinese Materia Medica, 2013, 38(3): 350-353
Authors:XIAO Hui-jun  LI Chen-yang  TANG Sheng-an  QIN Nan  DUAN Hong-quan
Affiliation:School of Pharmacy, Research Center of Basic Medical Sciences, Tianjin Key Laboratory on Technologies Enabling Development Clinical Therapeutics and Diagnostics, Tianjin Medical University, Tianjin 300070, China;School of Pharmacy, Research Center of Basic Medical Sciences, Tianjin Key Laboratory on Technologies Enabling Development Clinical Therapeutics and Diagnostics, Tianjin Medical University, Tianjin 300070, China;School of Pharmacy, Research Center of Basic Medical Sciences, Tianjin Key Laboratory on Technologies Enabling Development Clinical Therapeutics and Diagnostics, Tianjin Medical University, Tianjin 300070, China;School of Pharmacy, Research Center of Basic Medical Sciences, Tianjin Key Laboratory on Technologies Enabling Development Clinical Therapeutics and Diagnostics, Tianjin Medical University, Tianjin 300070, China;School of Pharmacy, Research Center of Basic Medical Sciences, Tianjin Key Laboratory on Technologies Enabling Development Clinical Therapeutics and Diagnostics, Tianjin Medical University, Tianjin 300070, China
Abstract:
Keywords:Pachysandra  Pachysandra terminalis  chemical constituent
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