| 吉林地区汉族人群4个Y-STR基因座的遗传多态性调查 |
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| 引用本文： | 庄文越,王雪松,张吉林,王冰梅.吉林地区汉族人群4个Y-STR基因座的遗传多态性调查[J].苏州大学学报(自然科学版),2009,29(6):1170-1172. |
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| 作者姓名： | 庄文越 王雪松 张吉林 王冰梅 |
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| 作者单位： | 庄文越,ZHUANG Wen-yue(北华大学检验学院分子生物学教研室,吉林吉林,132013;苏州大学医学部基础医学与生物科学学院,江苏);王雪松,WANG Xue-song(吉林市卫生局,卫生监督所,吉林吉林,132001);张吉林,王冰梅,ZHANG Ji-lin,WANG Bing-mei(北华大学检验学院分子生物学教研室,吉林吉林,132013) |
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| 摘 要： | 目的调查吉林地区汉族人群4个Y染色体短串联重复序列（Y-STR）基因座的遗传多态性。方法利用PCR扩增和聚丙烯酰胺凝胶电泳技术对吉林地区汉族群体无关男性血样进行4个Y-STR基因座的分型。结果4个Y-STR基因座在吉林地区汉族群体分别发现4～5个等位基因,GD值最低为0.645 1（DYS389I）,最高为0.716 7（DYS19）。结论4个Y-STR基因座在吉林地区汉族群体均具有较高的遗传多态性,可应用于法医学个体识别和亲子鉴定。
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| 关 键 词： | 短串联重复序列 Y染色体 遗传多态性 |
Study on Genetic Polymorphisms of 4 Y Chromosome Specific STR Loci in Jilin Han Population |
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| ZHUANG Wen-yue,WANG Xue-song,ZHANG Ji-lin,WANG Bing-mei.Study on Genetic Polymorphisms of 4 Y Chromosome Specific STR Loci in Jilin Han Population[J].Suzhou University Journal of Medical Science,2009,29(6):1170-1172. |
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| Authors: | ZHUANG Wen-yue WANG Xue-song ZHANG Ji-lin WANG Bing-mei |
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| Institution: | ZHUANG Wen-yue, WANG Xue-song, ZHANG Ji-lin , WANG Bing-mei (1. Dept of Molecular Biology, Ecsomatics School of Beihua University ,Jilin Jilin 132013, China; 2. Institute of Preclinical Medicine and Biology, Medical College, Soochow University, Jiangsu Suzhou 215123, China; 3. Hygiene Monitoring Institute of Public Health Bureau, Jilin Jilin 132001, China) |
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| Abstract: | Objective To study the genetic polymorphisms of 4 Y chromosome specific short tandem repeat （STR） loci in Jilin Han population. Methods The DNA extracted from blood samples of unrelated individuals in Han population living in Jilin were amplified by PCR. The PCR products were analyzed by using PAGE. Results Four to five alleles were detected in 4 Y-STR loci respectively in Han population in Jilin. The minimum GD value was 0. 6451 （DYS389I） , while the maximum GD value was 0. 7167 （DYS19）. Conclusion The 4 Y-specific STR loci are highly polymorphic and are suitable for personal identification and paternity testing. |
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| Keywords: | short tandem repeat Y chromosome genetic polymorphism |
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