麻痹性痴呆5例临床分析

目的:了解麻痹性痴呆的临床特点,为正确诊断提供依据。方法:以临床症状、实验室检查、辅助检查来做出正确诊断。结果:5例患者中,符合麻痹性痴呆夸大型1例、偏执型1例、痴呆型3例;血清学检查RPR、TRUST、TPPA均阳性5例,CT或MRI均示脑萎缩;诊断明确后均进行了大剂量青霉素驱梅治疗及对症治疗。结论:对出现精神障碍并发智能低下、性格改变的中年期患者,应结合病史及RPR、TRUST、TPPA检查、CT或MRI等做出正确诊断,以便采取有效治疗。

Clinical analysis of 5 patients with general paresis of insane

Objective:To understand the clinical features of general paresis of insane(GPI),provide the basis for the correct diagnosis.Methods:According to the clinical symptom,laboratory examination and auxiliary examination to make the correct diagnosis.Results:In 5 cases,1 cases with boast type of GPI,1 cases with paranoid type,3 cases with dementia type.5 cases of RPR,TRUST and TPPA of serological examination were positive,CT or MRI showed brain atrophy.After diagnosis was confirmed,large dose penicillin antisyphilitic treatment and symptomatic treatment were carried out.Conclusion:For the middle-aged patients with mental disorder complicated mental retardation and personality changes,should according to medical history,RPR,TRUST,TPPA and CT or MRI to make the correct diagnosis,in order to take the effective treatment.