Immunoglobulin G subclass deficiency and susceptibility to pyogenic infections in patients with AIDS-related complex and AIDS |
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| Authors: | J M Parkin M Helbert C L Hughes A J Pinching |
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| Affiliation: | Department of Immunology, St Mary's Hospital and Medical School, London, UK. |
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| Abstract: | Total immunoglobulin (Ig) and IgG subclass levels were measured in 72 patients with AIDS or AIDS-related complex (ARC). IgG2 subclass levels were found to be significantly decreased in the AIDS/ARC patients with pyogenic infections compared with both similar individuals without bacterial disease and the HIV-negative control group. |
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