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Biological effects of static magnetic fields on the microcirculatory blood flowin vivo: a preliminary report
Authors:Dr. S. Ichioka  M. Iwasaka  M. Shibata  K. Harii  A. Kamiya  S. Ueno
Affiliation:(1) Department of Plastic Surgery, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113 Tokyo, Japan;(2) Institute of Medical Electronics, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113 Tokyo, Japan
Abstract:There have been few studies of the effect of static magnetic fields on microcirculatory haemodynamics in vivo. The rat skinfold transparent chamber technique was used, which provides an excellent means of observing and quantifying direct in vivo microvascular haemodynamic responses to static magnetic fields up to 8 T. An intravital videomicroscope was used to measure the changes in blood flow before and after exposure to a magnetic field for 20 min in a horizontal type superconducting magnet with a bore 100 mm in diameter and 700 mm long. After exposure, microcirculatory blood flow showed an initial increase for about 5 min followed by a gradual decrease and a return to the control value. It is hypothesised that these changes represent rebound hyperaemia following reduced blood flow during exposure.
Keywords:Magnetic field exposure  Superconducting magnet  High-intensity magnetic field  Microcirculation  Haemodynamics  In vivo measurement  Rat transparent chamber  Intravital microscope
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