糖皮质激素联合高压氧治疗突发性耳聋的疗效观察

目的 观察和分析口服糖皮质激素联合高压氧治疗突发性耳聋的疗效.方法 经本院伦理学委员会批准和患者同意,143例（146耳）突发性耳聋患者分别采用口服糖皮质激素联合高压氧、单纯口服糖皮质激素、高压氧治疗,观察和比较3组治疗效果.结果 与单纯糖皮质激素或高压氧治疗组相比,糖皮质激素联合高压氧治疗组总有效率为81.3%（P〈0.05）.另外,单纯糖皮质激素治疗组（68%）疗效高于高压氧治疗组（56.3%）（P〈0.05）.结论 糖皮质激素联合高压氧治疗突发性聋的疗效显著,早期应用可提高疗效.

The Therapeutic Efficacy of Combination of Corticosteroid andHyperbaric Oxygen for Sudden Hearing Loss

Objective To observe the therapeutic efficacy of combination of corticosteroid and hyperbaric oxygen for sudden hearing loss. Methods 143 cases with sudden deafness were treated by combination of corticosteroid and hyper- baric oxygen （ CCH）, corticosteroid alone （ CA）, hyperbaric oxygen alone （ HA）, respectively. Results Total effective rate of CCH group （81.3% ） was significant increased comparing with corticosteroid alone （68%） or hyperbaric oxygen a- lone （56. 3% ） （P 〈0.05） ,and the effect of corticosteroid alone group was better on than hyperbaric oxygen alone （P 〈 0. 05）. Conclusion Patients with sudden hearing loss should be treated by combination of corticosteroid and hyperbaric oxygen as quickly as possible.