阿维A口服联合NB-UVB照射治疗寻常型银屑病疗效观察

目的观察阿维A胶囊口服联合NB-UVB照射治疗中、重度寻常型银屑病的疗效及安全性。方法对32例中、重度患者采用阿维A胶囊口服配合NB—UVB每周二次照射，共治疗8周，用PASI积分评价疗效，并记录不良反应。结果治疗开始1～2周后出现疗效，随着治疗时间的延长，有效率逐渐提高，治疗结束时痊愈率达到87．50％，有效率达96．88％。观察期间未见严重不良反应。结论阿维A胶囊口服联合NB—UVB照射治疗中、重度寻常型银屑病具有良好疗效和安全性。

Observation of therapeutic effect of oral acitretin combing with NB-UVB phototherapy with psoriasis vulgaris

Objective Observing therapeutic effect and safety phototherapy for moderate to severe psoriasis vulgaris. Methods property of oral acitret Oral acitretin combing wi in combing with NB-UVB th NB-UVB phototherapy on twice a week to treat 32 cases moderate to severe patients of psoriasis vulgaris, for 8 weeks. The efficacy was assessed by change in PASI seore and the adverse events were recorded. Results The efficacy appeared after the treatment in 1 to 2 weeks and the lesions were improved with time. At the end point, the results showed that the cure rate was 87.50% and the response rate was 96.88%. In the period of observation , serious side effects were not been found. Conclusions The current study demonstrates that the oral acitretin combing with NB-UVB phototherapy is effective and safe in the treatment in the moderate to severe psoriasis vulgaris.