微导管引流结合复方丹参注射液用于结核性胸腔积液的疗效观察

目的探讨微导管闭式引流结合复方丹参注射液治疗结核性胸腔积液的临床效果。方法150例中量以上积液的结核性胸膜炎病例分为3组,A组52例,胸腔置管引流并静脉滴注复方丹参注射液;B组50例,单纯置管引流;C组48例,常规胸腔穿刺抽液每周1~3次,观察各组患者的胸液引流量、胸液消失时间、体温变化以及2个月末胸膜增厚情况。结果A组胸液引流量中位数为1680ml,平均胸液消失时间(6.68±1.12)d,平均退热时间(3.8±1.1)d,2个月末胸膜增厚2例(3%);B组胸液引流量中位数为1415ml,平均胸液消失时间(8.88±2.42)d,平均退热时间(3.9±1.3)d,2个月末胸膜增厚8例(16%);C组胸液引流量中位数为880ml,平均胸液消失时间(15.23±11.56)d,平均退热时间(3.9±1.6)d,2个月末胸膜增厚12例(25%)。结论微导管引流胸腔积液结合复方丹参注射液治疗结核性渗出性胸腔积液的方法方便、安全、疗效满意,值得推广应用。

Observation of curative effect of micro-catheter drainage combined with compound radix salvia miltiorrhiza injection in treatment of tuberculosis thorax effusion

Objective To orobe into clinical effect of micro-catheter closed-type drainage combined with compound radix salvia miltiorrhiza injection in treating tuberculosis thorax effusion. Methods 150 cases of tuberculosis pleurisy patients who had more than medium-size of effusion were selected as the subject patients in the study. The patients were divided into three groups based on their timing of admission to the hospital. For the patients in Group A (n=52),thorax was inserted catheter for drainage and the patients were given by vein injection compound radix salvia miltiorrhiza; For Group B (n=50),catheter was simply inserted. For Group C (n=48),effusion in thorax was drained 1 to 3 times a week. All patients were observed and measured on their chest fluid drainage quantity,extinction time of chest fluid,changed body temperature,and thickening pleura at the end of the 2nd month. Results In Group A,B,and C,median chest fluid drainage quantity were,respectively,1680 ml,1415 ml and 880 ml; the mean extinction time of chest fluid were,respectively,6.68 d ( 1.12),8.88 d ( 2.42),and 15.23 d ( 11.56); the mean defeverscence were,respectively,3.8 d ( 1.1),3.9 d ( 1.3) and 3.9d ( 1.6); and the thickening pleura at the end of the 2nd month were,respectively,2 cases (3%),8 cases (16%),and 12 cases (25%). Conclusion The method of micro-catheter drainage combined with compound radix salvia miltiorrhiza injection in treating tuberculosis and exudative thorax effusion is convenient,safe and has satisfying curative effect. It is recommended for a wide use in clinic.