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| A novel LEN-derived β-lactamase from Klebsiela pneumoniae | |
| 引用本文： | Chen SW,Zhang RZ,Lu YM,He L,Wang SY,Mu XK. A novel LEN-derived β-lactamase from Klebsiela pneumoniae[J]. 中华医学杂志(英文版), 2005, 118(16): 1380-1383 |
| 作者姓名： | Chen SW Zhang RZ Lu YM He L Wang SY Mu XK |
| 作者单位： | [1]Division of Respiratory Medicine, Shenzhen People＇ s Hospital, Shenzhen 518020, China [2]Clinical Research Center, Shenzhen People＇ s Hospital, Shenzhen 518020, China [3]Microorganism Laboratory, Shenzhen People＇ s Hospital, Shenzhen 518020, China |
| 摘 要： | β-lactam antibacterial agents are the most commonly used antibiotics in clinic. The production of β-lactamases is the important mechanism for resistance to β-lactam antibiotics in Gram-negative bacteria. As a result of the generous use of β-lactam antibiotics, mutations of β-lactamases gene in bacteria are frequently developed to oppose against attack from antibiotics, novel β-lactamases were found one after another, among them SHV-28, CTX-M-11 and CTX-M-22 β-lactamases were first found by Chinese researchers. |
| 关 键 词： | β-内酰胺酶 抗生素 基因突变 压气学 |
| 收稿时间： | 2005-03-04 |
A novel LEN-derived beta-lactamase from Klebsiela pneumoniae |
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| Chen Sheng-wen,Zhang Ruan-zhang,Lu Yue-mei,He Lin,Wang Sha-yan,Mu Xue-kun. A novel LEN-derived beta-lactamase from Klebsiela pneumoniae[J]. Chinese medical journal, 2005, 118(16): 1380-1383 | |
| Authors: | Chen Sheng-wen Zhang Ruan-zhang Lu Yue-mei He Lin Wang Sha-yan Mu Xue-kun |
| Affiliation: | 1. Division of Respiratory Medicine,Shenzhen People's Hospital, Shenzhen 518020, China 2. Clinical Research Center,Shenzhen People's Hospital, Shenzhen 518020, China 3. Microorganism Laboratory,Shenzhen People's Hospital, Shenzhen 518020, China |
| Abstract: | |
| Keywords: | Klebsiela pneumoniae extended-Spectrum β-lactamase sequence analysis |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ | |
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