血清高密度脂蛋白及其亚组分胆固醇的临床分析

分析测定16例糖尿病，11例脑梗塞，45例高血压，26例冠心病，27例肝硬化，17例其他疾病（胃炎，慢支等）及63例正常人的血清高密度脂蛋白胆固醇（HDL－Ch)及其亚组分胆固醇（HDL2－Ch,HDL3-Ch)。结果：前五种疾病的HDL－Ch均显著降低（P＜0．01），其亚组分除糖尿病和高血压病的HDL3－Ch及肝硬化的HDL2－Ch无明显降低（P＞0．05）外，余项均显著降低（P＜0．01）。17例其他疾病的以上三项均值则无明显降低（P＞0．05）。提示：HDL－Ch及其亚组分的测定对动脉粥样硬化病变及肝脏病变的诊断具有重要的辅助意义。

Clinical Analysis of Serum HDL and Its Subcomponents Cholesterol

The serum HDL-Ch,HDL_2-Ch and HDL_3-Ch have been determined in sixteen patients with dia- betes,11 brain infarction,45 hypertension,26 coronary heart disease,27 liver cirrhosis,17 of othen diseases(gastritis,chronic bronchitis,etc.)and 63 normal subjects.The results showed:the mean values of HDL-Ch,HDL_2-Ch and HDL_3-Ch of the first five diseases were significantly lower than those of normal subjects(P<0.01),except that HDL_2-Ch of liver cirrhosis and HDL_3-Ch of diabetes and hy- pertension were not (P>0.05).The mean values of HDL-Ch,HDL_2-Ch and HDL_3-Ch of 17 patients with other diseases had no evident decrease(P>0.05).It is suggested that determination of HDL-Ch and its subcomponents has supplementary significance in the diagnosis of atherosclerosis and liver dis- eases.