| 丛状神经纤维瘤12例临床病理分析 |
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| 引用本文： | 吴礼高,刘德纯. 丛状神经纤维瘤12例临床病理分析[J]. 蚌埠医学院学报, 2007, 32(2): 156-158,F0004 |
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| 作者姓名： | 吴礼高 刘德纯 |
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| 作者单位： | 蚌埠医学院病理学教研室,安徽,蚌埠233030;蚌埠医学院病理学教研室,安徽,蚌埠233030 |
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| 摘 要： | 目的:探讨丛状神经纤维瘤的临床病理学特征. 方法:对12例丛状神经纤维瘤的临床表现、病理学特征进行观察和分析,并结合文献进行讨论. 结果:丛状神经纤维瘤一般在儿童期发病,好发头颈部、四肢和躯干.组织学表现为由schwann细胞、纤维母细胞及胶原纤维构成的丛状结构.免疫组化标记显示:梭形细胞以S-100蛋白阳性为主,vimentin、EMA、NsE或NF散在阳性. 结论:丛状神经纤维瘤有特殊的临床病理学特征,提高对丛状神经纤维瘤的认识有助于排查神经纤维瘤病1型.
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| 关 键 词： | 神经纤维瘤 丛状 神经纤维瘤病1型 病理学 临床 |
| 文章编号： | 1000-2200（2007）02-0156-03 |
| 修稿时间： | 2006-09-21 |
Plexiform neurofibroma:Clinicopathological analyses of 12 cases |
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| WU Li-gao,LIU De-chun. Plexiform neurofibroma:Clinicopathological analyses of 12 cases[J]. Journal of Bengbu Medical College, 2007, 32(2): 156-158,F0004 |
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| Authors: | WU Li-gao LIU De-chun |
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| Affiliation: | Department of Pathology,Bengbu Medical College ,Bengbu 233030, China |
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| Abstract: | Objective:To explore the clinicopathological features of plexiform neurofiroma(PNF).Methods:The clinical manifestatous and pathological charactors of 12 cases of PNF were observed and analysed combined with review of the literature.Results:PNF developed in childhood generally and often occurred at head and neck,limbs and trunks.The tumor appeared plexiform pattern consisted of Schwann cells,fibroblasts and collagen fibers.The spindle cells expressed S-100 protein diffusely and vimentin,EMA,NSE and NF scattered.Conclusions:PNF is a tumor with special clinicopathological characteristics,which is helpful to recognize the neurofibromatosis 1(NF1). |
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| Keywords: | neurofibroma, plexiform neurofibromatosis type 1 pathology, clinical |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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