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Contemporary developments in thin-layer chromatography
Authors:Wilson I D  Lewis S
Affiliation:

Drug Development, Hoechst Pharmaceutical Research Laboratories, Walton Manor, Walton, Milton Keynes, Bucks, MK7 7AJ, UK

Abstract:Qualitative and quantitative applications of thin-layer chromatography (TLC) in the biomedical and pharmaceutical fields are briefly surveyed. Some recent developments, including high-performance TLC (HPTLC) and reversed-phase TLC (RPTLC), together with techniques such as multiple development and continuous development, are considered. Instrumentation for HPTLC, and new developments in the detection and spectroscopic characterization of substances on TLC plates, are briefly described.
Keywords:Thin-layer chromatography   high-performance TLC   reversed-phase TLC   TLC—mass spectrometry   programmed multiple development in TLC   ion-pair TLC   radial TLC   overpressurized TLC.
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