外科围术期预防性应用抗菌药物干预对照研究

目的:评价干预措施对外科围术期抗菌药物合理应用的效果。方法:选取我院实施干预措施前(2006年7～12月)及干预后(2008年7～12月)外科手术病历各120例进行对照研究。结果:围术期抗菌药物合理应用率由干预前的0%上升至干预后的56.7%,干预后平均住院天数和术后平均用药天数均缩短(P<0.05),干预前存在的主要不合理用药现象得到显著改善。结论:我院实施的干预措施明显提高了合理用药水平,体现了干预措施的有效性和可行性。

Control Study of Intervention Measures for Perioperative Preventative Application of Antibiotic

OBJECTIVE： To evaluate the effect of intervention measures on perioperative preventative application of antibiotics. METHODS： 120 surgery patients in our hospital were collected and studied comparatively before （Jul. -Dec. of 2006） and after carrying out intervention measures （Jul.-Dec. of 2008）. RESULTS： The rational utilization rate of antibiotic during perioperative period increased from 0% （before intervention） to 56.7 % （after intervention）. Average admission day and average medication duration after operation both were shortened （P〈0.05）. Some major problems were improved significantly after intervention. CONCLUSIONS： The intervention measures advocated by our hospital promote the level of rational drug use and represent the feasibility and effectiveness of intervention measures.