| 下呼吸道感染患儿血清可溶性SIL－2R和免疫球蛋白IgG_4水平的研究 |
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| 引用本文： | 马京琪,诸小侬,张永珩,王红.下呼吸道感染患儿血清可溶性SIL－2R和免疫球蛋白IgG_4水平的研究[J].北京医学,1996(4). |
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| 作者姓名： | 马京琪 诸小侬 张永珩 王红 |
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| 作者单位： | 北京同仁医院儿科 |
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| 摘 要： | 对反复下呼吸道感染患儿的血清可溶性白细胞介素－２受体（ＳＩＬ－２Ｒ）和血清及唾液中免疫球蛋白（ＩｇＧ４）的水平进行了检测。结果表明：反复下呼吸道感染患儿在发病期间其血清可溶性白细胞介素－２受体水平比健康儿童明显升高（Ｐ＜０．０１），而血清及唾液中免疫球蛋白ＩｇＧ４与健康儿童相比明显降低（Ｐ＜０．０５和Ｐ＜０．００５），提示反复下呼吸道感染的小儿存在着细胞和体液免疫紊乱。
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| 关 键 词： | 血清可溶性白细胞介素－2受体（SIL－2R），免疫球蛋白G_4（IgG_4） |
A study of serum soluble interleukin-2 receptor and immunoglobulin G_4in children with recurrent lower respiratory tract infection |
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| Ma Jingqi,et al.A study of serum soluble interleukin-2 receptor and immunoglobulin G_4in children with recurrent lower respiratory tract infection[J].Beijing Medical Journal,1996(4). |
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| Authors: | Ma Jingqi |
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| Abstract: | Levels of serum soluble interleukin-2 receptor and immunoglobulin G4(both salivary and serum)were measured in 38 children with recurrent lower respiratory tract infection. The results revealed that levels of serum soluble interleukin-2 receptor were elevated during the course of the disease(P <0. 01), while serum and salivary IgG4 levels were lowered significantly as compared with those healthy children. It suggests that there is a T+B cell immunity functional disturbance in children with recurrent lower respiratory tract infection. |
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| Keywords: | Serum soluble interleukin-2 receptor(SIL-2R) Immunoglobulin G_4 (IgG_4) |
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