Electrophysiological observations in patients with motor neuron disease receiving a thyrotropin releasing hormone analogue (RX77368). |
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| Authors: | R J Guiloff E St?lberg D J Eckland S L Lightman |
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| Affiliation: | Department of Neurology, Westminster Hospital, Charing Cross and Westminster Medical School, London, UK. |
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| Abstract: | Twenty nine patients with motor neuron disease receiving a thyrotropin releasing hormone analogue showed acute 25-30% increase in mean corrected fibre density and mean macro EMG median amplitude and area in brachial biceps muscle. The data are consistent with a direct or indirect action of the drug on anterior horn cells. |
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