| 三联疗法治疗不稳定型心绞痛的疗效观察 |
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| 引用本文： | 黄超岚.三联疗法治疗不稳定型心绞痛的疗效观察[J].中国药房,2011(20):1864-1865. |
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| 作者姓名： | 黄超岚 |
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| 作者单位： | 浙江金华市人民医院心内科; |
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| 摘 要： | 目的:观察依诺肝素、氯吡格雷、阿司匹林联合治疗不稳定型心绞痛的疗效和安全性。方法:将2009年10月-2010年10月收治的100例不稳定型心绞痛患者随机均分为观察组和对照组。对照组给予阿司匹林起始剂量0.3g,之后0.1g,qd;氯吡格雷,负荷剂量300mg,然后75mg,qd,口服,6周为1个疗程。观察组在对照组基础上加用依诺肝素钠注射剂1mg·kg-1,q12h,皮下注射,持续应用3～7d。比较2组的治疗效果和不良反应发生情况。结果:观察组显效34例,有效15例,无效1例,总有效率为98.0%;对照组显效14例,有效22例,无效14例,总有效率为72.0%,2组总有效率比较差异有统计学意义(P<0.05)。观察组心绞痛复发、急性心肌梗死和心源性猝死等心脏事件的发生率显著低于对照组(P<0.05)。结论:依诺肝素、氯吡格雷、阿司匹林联合治疗不稳定型心绞痛疗效优于氯吡格雷、阿司匹林联合治疗,且不良反应比较无显著性差异。
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| 关 键 词： | 依诺肝素 氯吡格雷 阿司匹林 不稳定型心绞痛 疗效 |
Efficacy Observation of Triple Therapy in the Treatment of Unstable Angina |
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| HUANG Chao-lan.Efficacy Observation of Triple Therapy in the Treatment of Unstable Angina[J].China Pharmacy,2011(20):1864-1865. |
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| Authors: | HUANG Chao-lan |
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| Institution: | HUANG Chao-lan(Dept. of Cardiology, Jinhua People’s Hospital of Zhejiang Provice, Jinhua 321000, China) |
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| Abstract: | OBJECTIVE: To observe the therapeutic efficacy and safety of enoxaparin sodium combined with clopidogrel and aspirin in the treatment of unstable angina. METHODS: 100 patients suffering from unstable angina from Oct. 2009 to Oct. 2010 in our hospital were randomly divided into observation group and control group, with 50 patients in each group. The patients in the control group were treated with aspirin(loading dose 0.3 g, and then 0.1 g, qd) and clopidogrel(loading dose 300 mg, and then 75 mg, qd), 6 weeks... |
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| Keywords: | Enoxaparin sodium Clopidogrel Aspirin Unstable angina Therapeutic efficacy |
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