| 头孢米诺致药品不良反应文献分析 |
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| 引用本文： | 龙敏,陈蓉,王颖. 头孢米诺致药品不良反应文献分析[J]. 中国药房, 2011, 0(22): 2077-2079 |
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| 作者姓名： | 龙敏 陈蓉 王颖 |
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| 作者单位： | 成都市第六人民医院;成都市木综厂职工医院;四川省食品药品检验所; |
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| 摘 要： | 目的:探讨头孢米诺致药品不良反应(ADR)发生的特点及规律。方法:检索1990-2010年"中国医药期刊全文数据库"中有关头孢米诺临床应用及ADR个案报道的文献,得到符合条件的文献35篇共1474例,其中临床应用23篇1449例,个案报道12篇25例,并进行统计、分析、评价。结果:临床应用文献中,有84例记载ADR并分类,ADR发生率为5.80%,主要表现为消化系统反应(71.43%)、皮肤及其附件损害(19.05%)等。ADR个案报道为:急性肾损害(32.00%)、凝血障碍(20.00%)、皮肤及其附件损害(16.00%)等;以60岁以上的老年患者发生率最高(60.00%),约80.00%的ADR出现在用药3d后。结论:临床应重视头孢米诺引起的ADR,用药时应加强对患者的监护,以减少严重ADR的发生。
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| 关 键 词： | 头孢米诺 药品不良反应 文献 分析 |
Analysis of Adverse Drug Reactions Induced by Cefminox |
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| LONG Min CHEN Rong WANG Ying. Analysis of Adverse Drug Reactions Induced by Cefminox[J]. China Pharmacy, 2011, 0(22): 2077-2079 |
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| Authors: | LONG Min CHEN Rong WANG Ying |
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| Affiliation: | LONG Min(The Six People’s Hospital of Chengdu, Chengdu 610051, China) CHEN Rong(Staff-worker Hospital of Muzong Factory in Chengdu, Chengdu 610081, China) WANG Ying(Sichuan Institute for Food and Drug Control, Chengdu 610097, China) |
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| Abstract: | OBJECTIVE: To investigate the characteristics and regularity of ADR induced by cefminox. METHODS: ADR case reports and literatures about application of cefminox were retrieved from CHKD during 1990-2010. A total of 35 related literatures involving 1 474 cases, in which there were 23 literatures about clinical application of 1 449 cases and 12 individual case reports of 25 cases were analyzed statistically. RESULTS: Among literatures about clinical application, there were 84 ADR cases and the incidence of AD... |
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| Keywords: | Cefminox Adverse drug reactions Literatures Analysis |
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