| 23种中草药提取物对肺炎链球菌的抗菌作用研究 |
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| 引用本文： | 余琼,白志川,孟德胜,卢来春,张雪梅,傅若秋.23种中草药提取物对肺炎链球菌的抗菌作用研究[J].中国药房,2011(23):2135-2136. |
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| 作者姓名： | 余琼 白志川 孟德胜 卢来春 张雪梅 傅若秋 |
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| 作者单位： | 西南大学园艺园林学院;第三军医大学第三附属医院;重庆医科大学医学检验系; |
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| 摘 要： | 目的:研究23种中草药提取物对肺炎链球菌的体外抗菌活性。方法:采用96孔板培养法和涂片法测定23种中草药水、醇提取物的最低抑菌浓度(MIC)和最低杀菌浓度(MBC),采用药敏纸片法比较各提取物的抑菌圈大小。结果:三七、木瓜、黄芩等11种中草药对肺炎链球菌具有抗菌活性,其中三七、木瓜醇提物的抗菌作用最强,其MIC、MBC分别为1∶16、1∶8和1∶8、1∶4,抑菌圈直径分别为14mm和15mm。结论:三七、木瓜的醇提取物具有明显的抗肺炎链球菌作用。
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| 关 键 词： | 中草药 肺炎链球菌 最低抑菌浓度 最低杀菌浓度 |
Antibacterial Effects of 23 Kinds of Chinese Herbal Medicine Extracts on Streptococcus Pneumoniae |
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| YU Qiong,BAI Zhi-chuan MENG De-sheng,LU Lai-chun,FU Ruo-qiu ZHANG Xue-mei.Antibacterial Effects of 23 Kinds of Chinese Herbal Medicine Extracts on Streptococcus Pneumoniae[J].China Pharmacy,2011(23):2135-2136. |
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| Authors: | YU Qiong BAI Zhi-chuan MENG De-sheng LU Lai-chun FU Ruo-qiu ZHANG Xue-mei |
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| Institution: | YU Qiong,BAI Zhi-chuan(Horticulture and Landscape Architecture College of Southwest University,Chongqing 400715,China) MENG De-sheng,LU Lai-chun,FU Ruo-qiu(The Third Affiliated Hospital,Third Military Medical University,Chongqing 400042,China) ZHANG Xue-mei(Dept.of Laboratory,Chongqing Medical University,Chongqing 400016,China) |
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| Abstract: | OBJECTIVE:To evaluate the antibacterial activities of 23 kinds of Chinese herbal medicine extracts against Streptococcus pneumoniae(SPN) in vitro.METHODS:The minimal inhibitory concentration(MIC) and minimal bactericidal concentration(MBC) of 23 kinds of Chinese herbal medicine extract were determined by 96-well tissue culture microplates and smear method.The diameter of inhibition zone was compared using the Kirby-Baueer disc diffusion.RESULTS:11 kinds of Chinese herbal medicines had antibacterial activiti... |
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| Keywords: | Chinese herbal medicines Streptococcus pneumoniae Minimal inhibitory concentration Minimal bactericidal concentration |
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