| 秦皮中秦皮甲素的提取工艺研究 |
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| 引用本文： | 向小四,向大雄. 秦皮中秦皮甲素的提取工艺研究[J]. 中南药学, 2013, 11(4): 271-274,292 |
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| 作者姓名： | 向小四 向大雄 |
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| 作者单位： | 向小四 (中南大学湘雅二医院药学部,长沙410011;中南大学湘雅二医院湖南省中药制剂新技术重点研究室,长沙410011;中南大学药学院,长沙410013)； 向大雄 (中南大学湘雅二医院药学部,长沙410011中南大学湘雅二医院湖南省中药制剂新技术重点研究室,长沙410011中南大学药学院,长沙410013)； |
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| 摘 要： | 目的通过正交设计优化回流法提取秦皮中秦皮甲素的提取工艺。方法通过单因素及L9（34）正交试验优选秦皮中秦皮甲素的提取工艺。考察回流提取法中乙醇浓度、料液比、提取时间、提取次数、提取温度对秦皮甲素量的影响。结果最佳提取工艺条件为：乙醇浓度75%,料液比为1：10,提取温度为65℃,提取次数为4次,每次提取2 h。结论正交设计优化提取工艺可较好地提取秦皮中的秦皮甲素。
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| 关 键 词： | 秦皮 秦皮甲素 正交试验 提取工艺 |
Extraction of aesculin from Cortex Fraxini |
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| XIANG Xiao-si,XIANG Da-xiong. Extraction of aesculin from Cortex Fraxini[J]. Central South Pharmacy, 2013, 11(4): 271-274,292 |
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| Authors: | XIANG Xiao-si XIANG Da-xiong |
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| Affiliation: | 1. Department of Pharmacy, Second Xiangya Hospital, Central South Uni- versity, Changsha 41 O011; 2. Key Laboratory of Traditional Chinese Medicine Preparation, Second Xiangya Hos- pital, Central South University, Changsha 410011; 3. School of Pharmaceutical Sciences, Central South University, Changsha 410013) |
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| Abstract: | Objective To optimize the extraction of aesculin from Cortex Fraxini. Methods The extraction of aesculin from Cortex Fraxini was optimized by single factor and L9 （34） orthogonal design. The influences of alcohol concentration, solid- liquid ratio, extraction time, number of extraction, and extraction temperature on the content of aesculin were investigated. Results The optimum conditions were as follows： solid-liquid ratio 1 ： 10, extracting 4 times at 65 ℃, each time for 2 h with 75% ethanol. Conclusion The technics optimized by orthogonal design can extract aesculin from CortexFraxini. |
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| Keywords: | Cortex Fraxini aesculin orthogonal test extraction technology |
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