化学发光法检测性激素水平诊断继发性闭经

目的　探讨临床采用化学发光法诊断继发性闭经的准确性及其意义。方法　采用化学发光法检测 1 2 6例继发性闭经患者血清激素 ,共包括雌二醇 (E2 )、睾酮 (T)、孕酮 (P)、泌乳素 (PRL)、促黄体生成素 (LH)、促卵泡生成素 (FSH) 6项指标。结果　同正常对照组相比 ,闭经妇女的E2 、P明显降低 (P <0 .0 1 ) ,PRL有所上升 (P <0 .0 5 ) ,而T、LH、FSH则无明显改变。其中改变最明显的数据为E2 。结论　化学发光法诊断继发性闭经具有较高的准确性 ,是一种可行的临床检测方法

Diagnosis of the secondary amenorrhea by chemiluminoimmunoassay

Objective To study the accuracy of chemiluminoimmunoassay to diagnose secondary amenorrhea.Methods The serum hormone levels were measured by chemiluminoimmunoassay in 126 patients with secondary amenorrhea.Six serum hormones are estradiol(E 2),testosterone(T),progesterone(P),prolactin(PRL),luteinization(LH),follicle stimulating hormone(FSH).Results Compared with the contrast group,secondary amenorrhea women had high levels of PRL( P <0.05) and low levels of E 2 and P( P <0.01).Serum levels of T,FSH and LH had no significant change.Conclusion Chemiluminoimmunoassay is a good way for diagnosis of secondary amenorrhea.