The NEtherlands Cervical Kinematics (NECK) Trial. Cost-effectiveness of anterior cervical discectomy with or without interbody fusion and arthroplasty in the treatment of cervical disc herniation; a double-blind randomised multicenter study |
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Authors: | Mark P Arts Ronald Brand Elske van den Akker Bart W Koes Wilco C Peul |
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Institution: | (1) Department of Neurosurgery, Medical Center Haaglanden, The Hague, The Netherlands;(2) Department of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands;(3) Department of Medical Statistics & Bio Informatics, Leiden University Medical Center, Leiden, The Netherlands;(4) Department of Medical Decision Analysis, Leiden University Medical Center, Leiden, The Netherlands;(5) Department of General Practice, Erasmus Medical Center, Rotterdam, The Netherlands |
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Abstract: | Background Patients with cervical radicular syndrome due to disc herniation refractory to conservative treatment are offered surgical
treatment. Anterior cervical discectomy is the standard procedure, often in combination with interbody fusion. Accelerated
adjacent disc degeneration is a known entity on the long term. Recently, cervical disc prostheses are developed to maintain
motion and possibly reduce the incidence of adjacent disc degeneration. A comparative cost-effectiveness study focused on
adjacent segment degeneration and functional outcome has not been performed yet. We present the design of the NECK trial,
a randomised study on cost-effectiveness of anterior cervical discectomy with or without interbody fusion and arthroplasty
in patients with cervical disc herniation. |
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