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Importance of TNF-related apoptosis-inducing ligand in pathogenesis of interstitial cystitis

Authors:	Omer Kutlu Erdem Akkaya Ismail Turker Koksal Ibrahim Cumhur Bassorgun Mehmet Akif Ciftcioglu Salih Sanlioglu Erdal Kukul

Institution:	(1) Faculty of Medicine, Department of Urology, Akdeniz University, Antalya, 07070, Turkey;(2) Faculty of Medicine, Department of Pathology, Akdeniz University, Antalya, 07070, Turkey;(3) Faculty of Medicine, Department of Human Gene Therapy Unit, Akdeniz University, Antalya, 07070, Turkey;(4) Faculty of Medicine, Department of Medical Biology and Genetics, Akdeniz University, Antalya, 07070, Turkey;

Abstract:	Introduction Although interstitial cystitis is an inflammatory disease, its etiopathogenesis is not clearly understood. The objective of the present study is to investigate the distribution of TNF-related apoptosis-inducing ligand (TRAIL) and its receptors in bladder biopsy samples of patients diagnosed with interstitial cystitis and the role of TRAIL in the pathogenesis of interstitial cystitis.

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