溶药用注射针头及药液瓶橡胶塞微粒污染影响的研究

对临床静脉滴注溶药用的注射针头、药液瓶所用新旧橡胶塞的微粒污染影响进行了实验研究。结果表明：注射针头产生的微粒污染与针头的使用频率呈正相关，故建议使用一次性针头。对不同结构的两种插瓶用针头（斜面针头、侧孔针头）的观察表明，在使用中两者造成的微粒污染类似、差异无显著性。对药液瓶所用新旧橡胶塞的测定结果表明，在有绦纶膜保护的条件下，新旧橡胶塞所产生的微粒污染差异无显著性，这为旧橡胶塞的合理重复使用提供了实验依据。

The Study on Contamination of Particles Produced by Syringe Needles and Rubber Stoppers for Pharmacal Solution

The contamination of particles produced by syringe needles and rubber stoppers for pharmacal solution of venous transfusion was studied. The results showed that the contamination of particles was positive correlation with the usage frequency of syringe needles,so the syringe needles for single use were suggested. To compare two kinds of syringe needles with different structure (side hole and incline),the result was that the difference of particle contamination between them was similar and without statistic significance. The particles contamination produced by primary and used rubber stoppers which was protected by polyester film was studied. It was showed that the difference between them was no significant statistically. The results of this study supplyed a scientific evidence about repeatedly use of rubber stoppers.