| Benign intracranial hypertension: atypical presentation of Miller Fisher syndrome? |
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| 引用本文： | Mewasingh LD,Sékhara T,Dachy B,Djeunang MC,Dan B.Benign intracranial hypertension: atypical presentation of Miller Fisher syndrome?[J].Pediatric Neurology,2002,26(3):228-230. |
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| 作者姓名： | Mewasingh LD Sékhara T Dachy B Djeunang MC Dan B |
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| 摘 要： |
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| 收稿时间： | 7 June 2001 |
Benign intracranial hypertension: atypical presentation of Miller Fisher syndrome? |
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| Mewasingh Leena D,Sékhara Tayeb,Dachy Bernard,Djeunang Maurice C,Dan Bernard.Benign intracranial hypertension: atypical presentation of Miller Fisher syndrome?[J].Pediatric Neurology,2002,26(3):228-230. |
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| Authors: | Mewasingh Leena D Sékhara Tayeb Dachy Bernard Djeunang Maurice C Dan Bernard |
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| Institution: | 1. Department of Neurology, Hôpital Universitaire des Enfants Reine Fabiola, 1020 Brussels, Belgium;2. Department of Clinical Neurophysiology, Hôpital Brugmann, 1020 Brussels, Belgium;1. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas;2. Texas Children’s Hospital, Houston, Texas;3. Cancer Genetics, UT Southwestern Medical Center, Dallas, Texas;4. Ambry Genetics, Aliso Viejo, California;5. Department of Pediatrics, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas;1. Senior Resident, Employee’s State Insurance- Postgraduate Institute of Medical Science and Research, Basaidarpur, New Delhi, India;2. Senior Resident, Pediatric Neurology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India;3. Junior Resident, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India;4. Assistant Professor, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India;1. New York University School of Medicine, New York, New York;2. Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York;1. Department of Neurology, SUNY Downstate Health Sciences University, New York, New York;2. Department of Pediatrics (Neurology), Maimonides Medical Center, New York, New York;3. Department of Neurology, University of Texas Dell Medical School, Austin, Texas;1. Department of Psychology, St. Louis Children’s Hospital, St. Louis, Missouri;2. Department of Neurology, Washington University School of Medicine, St. Louis, Missouri;3. Department of Neurology, St. Louis Children’s Hospital, St. Louis, Missouri |
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| Abstract: | Acute ocular paresis, nausea, vomiting, and headaches associated with high intracranial pressure without obvious intracranial pathology are typical features of benign intracranial hypertension. We describe two young children whose presentation, initially suggestive of idiopathic or benign intracranial hypertension, evolved to comprise ophthalmoplegia, ataxia, and areflexia. This triad characterizes Miller Fisher syndrome, a clinical variant of Guillain-Barré syndrome that occurs rarely among children. In both patients, this diagnosis was supported by the clinical course and neurophysiologic findings. Plasma serology was positive for Campylobacter jejuni and anti-GQ1b antibodies in one patient and for antimyelin antibodies in the other. This report of two children with Miller Fisher syndrome presenting with intracranial hypertension adds to the findings for a similar patient treated previously, which raises the question concerning the possible role or contribution of benign intracranial hypertension in Miller Fisher syndrome. |
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