| 血液稀释对急性心肌梗塞兔循环功能及心肌应激性的影响 |
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| 引用本文： | 孙运波,王保平,王世端,于文刚,高绪孟. 血液稀释对急性心肌梗塞兔循环功能及心肌应激性的影响[J]. 潍坊医学院学报, 1994, 0(1) |
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| 作者姓名： | 孙运波 王保平 王世端 于文刚 高绪孟 |
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| 作者单位： | 青岛大学医学院附院麻醉科，济宁医学院血液稀释研究所 |
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| 摘 要： | 取家兔１６只，冠状动脉左室支结扎后均分为血液稀释组（ＨＤ）和正常红细胞压积（Ｈｃｔ）组（ＮＧ）。另取兔８只仅行开胸手术作为对照组（ＣＧ）。观察血液稀释对心肌梗塞兔循环。肾上腺素诱发室性心律失常剂量（Ｅ／Ｖ）及梗塞区大小的影响。结果Ｈｃｔ：ＨＤ３１．３±２．７％，ＮＧ３８．１±２．６２％，ＣＧ３９．１±１．６％。冠状动脉结扎后至半小时内三组ＨＲ，ＭＡＰ，ＣＶＰ及心肌耗氧量均明显增加。ＨＤ的增加达１ｈ（Ｐ＜０．０５）。（ＥＩＶ：ＣＯ２３．３±４．５μｇ·ｋｇ－１，ＨＤ１８．０±２．９５μｇ·ｋｇ－１（Ｐ＞０．０５），ＮＧ，６．８６±１．７μｇ·ｋｇ－１，差异显著（Ｐ＜０．０５）。心肌梗塞区占全心重ＨＤ为６．４％，ＮＧ８．１％。（Ｐ＞０．０５）。证实血液稀释有提高心肌应激性，成少室性心律失常，改善心肌微循环和减小梗塞范围的功效。
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| 关 键 词： | 血液稀释，心肌梗塞，心肌应激性 |
THE EFFICACY OF HEMODILUTION ON THE CIRCULATION OF ACUTE MYOCARDIAC INFARCTION AND THE STRESS OF MYOCARDIUM IN RABBITS |
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| Sun Yunbo, Wang Baoping, Wang Shiduan,et al.. THE EFFICACY OF HEMODILUTION ON THE CIRCULATION OF ACUTE MYOCARDIAC INFARCTION AND THE STRESS OF MYOCARDIUM IN RABBITS[J]. Journal of Weifang Medical College, 1994, 0(1) |
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| Authors: | Sun Yunbo Wang Baoping Wang Shiduan et al. |
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| Affiliation: | Dept. of Anesthesology of affiliated Hospital of Qingdao Medical College |
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| Abstract: | The model of acute myocadiac infarction in sixteen rabbits were established by occlusion of left ventricular coronary artery and hemodil ution were porformed. Hematocrit was reduced to 31.3%. It proved that hemodilution can enhance the myocardiac stress and improve the myocardiac microcirculation, Lessening the area of infarction, and protecting against ventricular arrythmia. It may be benificial for the acute myocadiac infarction. But It must be paid great attention to avoid the side effects of sympathetic excitement and tachycardia. |
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| Keywords: | hemodilution myocadiac infarction myocadium stress |
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