| Cell biology in orthodontic tooth movement： The known and the unknown |
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| 引用本文： | RENYi-jin. Cell biology in orthodontic tooth movement： The known and the unknown[J]. 上海口腔医学, 2005, 14(2): 182-189 |
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| 作者姓名： | RENYi-jin |
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| 作者单位： | DepartmentofOrthodontics,UniversityMedicalCentreGroningen.TheNetherlands |
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| 摘 要： | This review is aimed at providing, at the cellular level, a concise and complete overview ot the important knowledge on the mechanism of orthodontic tooth movement to orthodontists and postgraduates who are involved or interested in basic research. The construction of this article was oriented to the following key questions: Where an osteoclast starts to its first resorption site? When the cascade of a resorption cycle starts? What are the factors involved in bone remodeling and how they orchestrate? What happens before and after the formation of a resorption pit? Major findings in these aspects were summarized and discussed. In addition, related biological phenomenon such as orthodontically induced root resorption was intensively reviewed. By means of an updated and systematic review, the author intended to introduce more biological evidence to orthodontic intervention and to encourage evidence-based treatment in daily orthodontic practice.
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| 关 键 词： | 细胞生物学 牙疾病 牙科医生 治疗 破骨细胞 |
| 文章编号： | 1006-7248(2005)02-0182-08 |
| 修稿时间： | 2004-11-02 |
Cell biology in orthodontic tooth movement: The known and the unknown |
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| REN Yi-jin. Cell biology in orthodontic tooth movement: The known and the unknown[J]. Shanghai journal of stomatology, 2005, 14(2): 182-189 |
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| Authors: | REN Yi-jin |
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| Affiliation: | Department of Orthodontics, University Medical Centre Groningen. The Netherlands |
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| Abstract: | This review is aimed at providing, at the cellular level, a concise and complete overview of the important knowledge on the mechanism of orthodontic tooth movement to orthodontists and postgraduates who are involved or interested in basic research. The construction of this article was oriented to the following key questions: Where an osteoclast starts to its first resorption site? When the cascade of a resorption cycle starts? What are the factors involved in bone remodeling and how they orchestrate? What happens before and after the formation of a resorption pit? Major findings in these aspects were summarized and discussed. In addition, related biological phenomenon such as orthodontically induced root resorption was intensively reviewed. By means of an updated and systematic review, the author intended to introduce more biological evidence to orthodontic intervention and to encourage evidence-based treatment in daily orthodontic practice. |
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| Keywords: | Orthodontics Tooth movement Osteoclast RANIC/RANICL/OPG Root resorption |
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