过敏性鼻炎-哮喘综合征治疗方法的成本效果分析

目的:探讨过敏性鼻炎-哮喘综合征治疗方法的成本效果,从而选择合理的治疗药物。方法:过敏性鼻炎-哮喘综合征患者200例根据药物应用的不同分为糖皮质激素组(A组)、抗组胺组(B组)、白三烯受体拮抗剂组(C组)、抗-IgE单克隆抗体组(D组)和转移因子组(E组),分别应用相应的药物治疗。结果:D组与E组的有效率都高于A组、B组、C组(P<0.05),D组与E组的成本明显高于A组、B组、C组(P<0.05),A组与C组的C/E值明显少于其他三组(P<0.05),进行敏感度分析,表明影响因素在一定的变化范围内并不影响结果。结论:糖皮质激素法与白三烯受体拮抗剂法是治疗过敏性鼻炎-哮喘综合征的最佳治疗方法,值得推广应用。

The Cost-effectiveness analysis of the treatment of allergic rhinitis-asthma syndrome

Objective To investigate the cost-effectiveness of allergic rhinitis-asthma syndrome treatment for reasonable choice of treatment drugs.Methods 200 cases of allergic rhinitis-asthma syndrome patients were equally divided into glucocorticoid group(A),the anti histamine group(B),leukotriene receptor antagonist group(C group),anti-IgE monoclonal antibody group(D) and transfer factor group(E) depending on the drug application respectively,there were appled the appropriate medication.Results Group D and E efficiency were higher than A,B,C group(P <0.05),D group and E group cost were significantly higher than the A,B,C group(P<0.05),group A and group C C/E values significantly were less than the other three groups(P<0.05),sensitivity analysis showed that the influencing factors can not affect the results.Conclusion The glucocorticoid law and leukotriene receptor antagonists are the best treatment for the treatment of allergic rhinitis-asthma syndrome,should be widely applied.