Bacterial resistance to trimethoprim in geriatric medical wards |
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| Authors: | M J Bendall S Ebrahim R G Finch R C Slack K J Towner |
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| Affiliation: | Department of Health Care of the Elderly, University of Nottingham Medical School, UK. |
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| Abstract: | Urinary tract infections (UTI) caused by organisms resistant to trimethoprim (TMP), as well as their faecal carriage were studied in two geriatric wards. TMP-resistant UTI was common (26 and 50% of admission and ward-acquired infections, respectively) and was associated with male sex, recurrent and transferred admissions and length of stay. There was a strong relationship between faecal carriage and isolation of TMP-resistant organisms from urine. Antimicrobial exposure was the major determinant of TMP-resistant faecal carriage. |
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