双黄连注射液与10％葡萄糖注射液配伍研究

目的：探讨双黄连注射液与10％葡萄糖注射液的适宜配伍浓度。方法：用10mL、20mL、25mL、30mL及35mL双黄连注射液，分别与200mL10％葡萄糖注射液配伍，观察其在4h内微粒变化，在4h内的pH值、紫外吸收的变化。结果：20mL及以下配伍液放置4h以内。微粒符合药典规定，pH值无明显变化；25mL及以上配伍液微粒不符合药典规定。结论：20mL及以下双黄连注射液与10％葡萄糖注射液配伍在4h内可以应用。

Study on combination of Shuanghuanglian Injection and 10% Glucose Injection

：Objective ：To study the Appropriate concentration compatibility of shuanghuanglian Injection mixed with 10% Glucose Injection in clinical application. Methods： 200 ml 10% Glucose Injection mixed with 10 ml,20 ml,25 ml,30 ml,35 ml shuanghuanglian Injection separately, observing the change of appearance, particles 4h after mixing, the change of PH value, UV absorption 4 h after mixing. Results： No significant change was noted in appearance, PH value and the particles were meet the pharmacopoeia in the mix- ture 20ml and the below within 4 h after mixing; the particles did not meet the pharmacopoeia in the mixture 25 ml and the above. Conclusion： Shuanghuanglian Injection and 10% Glucose Injection could be mixed to use in 25 ml the below within 4 h.