右美托咪定用于腰-硬联合麻醉中的镇静效果

目的 探讨右美托咪定在腰-硬联合麻醉中镇静效果.方法 将122例需手术患者分为观察组61例和对照组61例,分别运用右美托咪定、咪唑安定.结果 观察组用药后MAP (97.0±9.2)mmHg、HR(61.0±9.3)次/min低于用药前(P＜0.05),但Sp02下降不明显(P＞0.05);T2～T4,对照组MAP[(112.6±10.9)mmHg、(114.4±7.5) mmHg、(115.6±9.2) mmHg]高于观察组[(97.0±9.2)mmHg、(93.6±8.4)mmHg、(92.3±11.3) mmHg],T2～T5,两组Ramsay评分均高于T0,且观察组Ramsay高于对照组(P＜0.05).结论右美托咪定在腰-硬联合麻醉中应用镇静效果显著.

Sedative effect of spinal-epidural anesthesia with dexmedetomidine

Objective To explore the sedative effect of spinal-epidural anesthesia with dexmedetomidine.Methods 122 surgically treated patients were divided into an observation group and a control group,61 cases for each group.The observation group were given dexmedetomidine and the control group midazolam.Results After drug use,the MAP and HR were (97.0±9.2)mmHg and (61.0±9.3) beats/min in the observation group and were lower than those before drug use but the SpO2 did not decreased obviously (P＜0.05).T2-T4,the MAP were (112.6410.9)mmHg,(114.4±7.5) mmHg,and (115.6±9.2) mmHg in the control group and were (97.0±9.2) mmHg,(93.6±8.4) mmHg,and (92.3±11.3) mmHg in the observation group.T2-Ts,Ramsay scores were higher than those at T0 in both groups and in the observation group than in the control group (P＜0.05).Conclusion The sedative effect of spinal-epidural anesthesia with dexmedetomidine is remarkable.