斛柏粉敷脐控制乳腺癌化疗所致恶心呕吐疗效观察

目的 观察斛柏粉敷脐控制乳腺癌化疗所致恶心呕吐的效果.方法 将89例经病理确诊乳腺癌术后接受化疗的患者随机分为观察组(n=45)和对照组(n=44).对照组于化疗前30 min静脉滴注3 mg格拉司琼止吐;观察组在应用格拉司琼的同时,于化疗前晚用备好的斛柏粉10 g外敷于神阙穴,每晚换药1次,至化疗结束后次晨停用.结果 观察组急性呕吐发生率为28.9％,明显低于对照组的52.3％(x2=5.050,P=0.025);迟发性呕吐发生率为15.6％,明显低于对照组的34.1％(x2=4.107,P=0.043).观察组食欲明显好于对照组,0～Ⅰ度发生率比较,差异有统计学意义(x2=8.217、4.047,P=0.004、0.044,);Ⅱ～Ⅲ度发生率比较,差异无统计学意义.结论 斛柏粉敷脐对乳腺癌化疗所致恶心呕吐有较好的控制效果.

Umbilical therapy of Hubo powder in treatment of nausea and vomiting caused by chemotherapy for breast carcinoma

Objective To observe the effect of umbilical therapy of Hubo powder in the treatment of nausea and vomiting caused by chemotherapy for breast carcinoma.Methods 89 patients conformed with breast cancer by pathological diagnosis were randomly divided into an observation group (n=45) and a control group (n=44).The control group were intravenously dripped 3 mg granisetron 30 min before chemotherapy;in addition,the observation group took umbilical therapy of 10 g Hubo powder from the night before chemotherapy until the chemotherapy was over,once per night.Results The incidence of acute vomiting was significantly lower in the observation group than in the control group (28.9％ vs.52.3％,x2=5.050,P=0.025).The incidence of delayed vomiting was significantly lower in the observation group than in the control group (15.6％vs.34.1％,x2=4.107,P=0.043).The patients' appetite was significantly better in the observation group than in the control group,with statistical difference in the incidences of 0 and Ⅰ degrees (x2=8.217,4.047,P=0.004,0.044) but no in the incidences of Ⅱ and]Ⅲ degrees.Conclusion Umbilical therapy of Hubo powder in the treatment of nausea and vomiting caused by chemotherapy for breast carcinoma is effective.