Transfusion associated graft versus host disease in immunocompetent patients. Report of two cases |
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| Authors: | Gebran N Aoun J P Aftimos G Debahy N Chamseddine N Hakimeh N Bahous J |
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| Affiliation: | Saint-Georges Hospital, Beirut (SGH), Lebanese University School of Medicine, Lebanon. |
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| Abstract: | Transfusion graft versus host disease (TGVHD) in immunocompetent patients is a recently recognized disease, reported mainly after open heart surgery, and almost always fatal. We report two cases of TGVHD in immunocompetent patients after open-heart surgery. The disease is characterized by the occurrence of fever, skin rash, liver failure and pancytopenia. Preventive measures include exclusion of first- and second-degree relatives as blood donors, and/or irradiation of blood to be transfused. |
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