| 泌尿生殖道沙眼衣原体临床株体外药物敏感性检测及分析 |
| |
| 引用本文： | 吴志周,祝新,杨日好,柯建良,黄澍杰. 泌尿生殖道沙眼衣原体临床株体外药物敏感性检测及分析[J]. 医学理论与实践, 2011, 24(15): 1777-1778,1786 |
| |
| 作者姓名： | 吴志周 祝新 杨日好 柯建良 黄澍杰 |
| |
| 作者单位： | 广东省江门市皮肤医院,529000 |
| |
| 摘 要： | 目的:检测江门地区泌尿生殖道沙眼衣原体临床分离株对强力霉素、四环素和左氧氟沙星等8种临床常用抗生素的体外药物敏感性。方法:McCoy细胞培养法分离沙眼衣原体临床株,测定8种抗生素对沙眼衣原体的最低抑菌浓度(MIC)。结果:共培养出沙眼衣原体阳性株100株,经传代培养至感染率达90%以上符合药敏试验所需菌量的菌株有73株;MIC值范围分别为强力霉素0.016~0.125μg/ml、四环素0.039~0.625μg/ml、阿奇霉素0.032~1μg/ml、交沙霉素0.005~0.16μg/ml、红霉素0.125~2μg/ml、克拉霉素0.004~0.064μg/ml、左氧氟沙星0.063~1.0μg/ml和司帕沙星0.032~0.256μg/ml。结论:克拉霉素及阿奇霉素有较强的抗菌活性,强力霉素次之,红霉素和左氧氟沙星的抗菌活性则较低。
|
| 关 键 词： | 沙眼衣原体 药物敏感性 最低抑菌浓度 |
The Detection and the Susceptibility Analysis to Antimicrobial Agants of Urogenital Chlamydial Trachomatis Infection |
| |
| WU Zhizhou,ZHU Xin,YANG Rihao,et al.. The Detection and the Susceptibility Analysis to Antimicrobial Agants of Urogenital Chlamydial Trachomatis Infection[J]. The Journal of Medical Theory and Practice, 2011, 24(15): 1777-1778,1786 |
| |
| Authors: | WU Zhizhou ZHU Xin YANG Rihao et al. |
| |
| Affiliation: | WU Zhizhou,ZHU Xin,YANG Rihao,et al.Demartological Hospital of Jiangmen City,Guangdong Province 529000 |
| |
| Abstract: | Objective:To assess the vitro susceptibility to 8 antimicrobial agents of clinical isolates of Chlamydia trachomatis(Ct) from Jiangmen region.Methods:Ct was isolated from clinical specimens by using McCoy cell culture and subjected to propagation.The minimum inhibitory concentration of 8 antimicrobial agents(Doxycycline,Tetracycline,Azithromycin,Josamycin,Erythrocin,Clarithromycin,Levofloxacin and Sparfloxacin)against Ct isolates were determined.Results:A total of 100 clinical strains were isolated from cer... |
| |
| Keywords: | Chlamydia trachomatis Microbial sensitivity tests Minimum inhibitory concentration |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
