大分子乳化剂对复乳稳定性的影响及应用 |
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引用本文: | 徐成业,陈亭亭,陆伟根.大分子乳化剂对复乳稳定性的影响及应用[J].中国医药工业杂志,2011,42(6). |
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作者姓名: | 徐成业 陈亭亭 陆伟根 |
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作者单位: | 中国医药工业研究总院药物制剂国家工程研究中心,上海,200437 |
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基金项目: | 上海市科学技术委员会生物医药重点科技项目 |
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摘 要: | 综述了大分子乳化剂改善复乳稳定性的作用机制及其在复乳中的应用现状.复乳是复杂的液体分散体系,为热力学不稳定系统,易发生分层、絮凝和合并,通常加入单体乳化剂以提高其稳定性.近年来大分子乳化剂如生物聚合物、嵌段聚合物、高分子乳化剂因能较好地改善复乳稳定性,在复乳中得到广泛应用.
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关 键 词: | 复乳 大分子乳化剂 稳定性 综述 |
Effects of Macromolecular Emulsifiers on Double-emulsions Stability and Application |
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Authors: | XU Chengye CHEN Tingting LU Weigen |
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Institution: | XU Chengye,CHEN Tingting,LU Weigen(National Pharmaceutical Engineering Research Center,China State Institute of Pharmaceutical Industry,Shanghai 200437) |
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Abstract: | In this paper the mechanism of double-emulsions stability improved by macromolecular emulsifiers as well as the applications of macromolecular emulsifiers in the double-emulsions are reviewed.Double-emulsions are complex liquid dispersion systems,which are inherent thermodynamic unstable systems and tend to delaminate,flocculate and coalesce.Double-emulsions are usually stabilized by adding monomeric emulsifiers.In recently years,macromolecular emulsifiers such as biopolymers,block copolymers and polymeric ... |
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Keywords: | double-emulsions macromolecular emulsifier stability review |
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