甲磺酸帕珠沙星治疗急性呼吸道感染的疗效观察

目的评价甲磺酸帕珠沙星治疗急性呼吸道感染的疗效。方法选择符合诊断标准的患者122例,随机分为2组(各61例),实验组应用甲磺酸帕珠沙星注射液,对照组应用盐酸左氧氟沙星氯化钠注射液。结果实验组的痊愈率、有效率为70.49%、98.36%,对照组为63.93%、93.44%;实验组的细菌清除率为100%,对照组为98.04%;实验组的不良事件发生率为8.2%,对照组为3.28%,均无显著性差异(P>0.05)。结论甲磺酸帕珠沙星在治疗急性呼吸道感染中有较好的临床疗效和安全性。

The therapeutic effect of pazufloxacin mesilate on acute respiratory infection

Objective To evaluate the effect of pazufloxacin mesilate on acute respiratory infection. Methods One hundred and twenty two patients were randomized to two groups, the trial group used pazufloxacin mesylate injection, and the control group used levofloxacin sodium chloride injection. Results The cured rate and effective rate of trial group were 70.49 % and 98.36 %, while those of control group were 63.9 % and 93.44 %. The bacterial eradication rate of two groups were 100 % and 98.04 %, and the incidence of adverse reaction were 9.2 % and 3.28 % respectively. There was no significant difference between them. Conclusion Pazufloxacin has excellent therapeutic effect on acute respiratory infections, and it also has good safety.