| 超长方案在卵巢储备良好前次IVF/ICSI-ET失败患者中的应用分析 |
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| 引用本文： | 聂玲,伍琼芳,张寅,陈晶晶. 超长方案在卵巢储备良好前次IVF/ICSI-ET失败患者中的应用分析[J]. 现代妇产科进展, 2011, 20(6): 470-472 |
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| 作者姓名： | 聂玲 伍琼芳 张寅 陈晶晶 |
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| 作者单位： | 1. 南昌大学医学院,南昌,330006
2. 江西省妇幼保健院生殖中心 |
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| 摘 要： | 目的:评估超长降调节方案在卵巢储备良好前次IVF/ICSI-ET失败患者中的应用效果。方法:回顾分析246例卵巢储备功能良好前次IVF/ICSI-ET常规长方案失败再次行助孕治疗的患者,其中超长方案治疗52例为研究组,常规长方案治疗194例为对照组。结果:研究组Gn时间及获卵数均高于对照组(P<0.01);但优质胚胎数、Gn量、注射HCG日孕酮水平、移植日子宫内膜厚度、中-重度OHSS发生率与对照组比较均无明显统计学差异(P>0.05);研究组HCG阳性率、临床妊娠率均明显高于对照组,分别是:79.1%vs 61.1%,P=0.03;69.8%vs 54.9%,P=0.048,胚胎种植率有上升趋势(39.5%vs 31.5%,P=0.18)。结论:在前次卵巢反应良好IVF/ICSI-ET失败患者中超长方案较长方案子宫内膜容受性可能更好,妊娠结局明显改善,是值得推荐的治疗方案。
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| 关 键 词： | 超长方案 体外受精-胚胎移植 促性腺激素释放激素激动剂 子宫内膜容受性 胚胎种植率 临床妊娠率 |
Clinical outcomes of prolonged gonadotropin-releasing hormone agonist(GnRH-a) therapy used in patients with good ovarian reserves and previous in vitro fertilization or intracytoplasmic sperm injection embryo transfer(IVF/ICSI-ET) failure cycle. |
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| Nie Ling,Wu Qiongfang,Zhang Yin,et al.. Clinical outcomes of prolonged gonadotropin-releasing hormone agonist(GnRH-a) therapy used in patients with good ovarian reserves and previous in vitro fertilization or intracytoplasmic sperm injection embryo transfer(IVF/ICSI-ET) failure cycle.[J]. Current Advances In Obstetrics and Gynecology, 2011, 20(6): 470-472 |
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| Authors: | Nie Ling Wu Qiongfang Zhang Yin et al. |
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| Affiliation: | Nie Ling1,Wu Qiongfang2,Zhang Yin1,et al.1.Medical College of Nanchang University,Nanchang 330006,2.Reproductive Medicine Center,Jiangxi Maternal and Child Health Hospital |
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| Abstract: | Objective:To evaluate the clinical outcomes of prolonged gonadotropin-releasing hormone agonist therapy(GnRH-a) used in patients with good ovarian reserves and previous in vitro fertilization or intracytoplasmic sperm injection embryo transfer(IVF/ICSI-ET) failure cycle.Methods:Retrospective analyze a total of 246 patients with previous IVF-ET failure cycle and good ovarian reserve who underwent the secondary IVF-ET cycles.Patients were divided into two groups:the study group included 52 patients applied wi... |
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| Keywords: | Prolonged protocol In vitro fertilization-embryo transfer Gonadotropin-releasing hormone agonist Endometrium receptivity Embryo implantation rate Clinical pregnancy rate |
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